Fate at Long-term of Mild to Moderate Bicuspid Aortic Valve Disease Left Untreated at the Time of Supracoronary Ascending Aorta Replacement

Michele De Bonis

Status: Completed

Conditions: Bicuspid Aortic Valve; Ascending Aorta Aneurysm

Treatments: Procedure: Ascending aorta replacement

Study type: Observational

Funder types: Other

Identifiers

NCT05836363

NO SVAO-BAV

Details and patient eligibility

About

Aortic valve bicuspid disease is the most common congenital heart disease. It affects 0.5-2% of the population and is associated with an increased risk of developing aortic or ascending aortic valve complications.

There is no agreement regarding the opportunity for a "prophylactic" simultaneous aortic valve replacement in the case of mild or moderate aortic valve disease in the bicuspid valve, in patients with an indication for replacement of the ascending aorta due to an aneurysm involving its supra-coronary tract.

The aim of this study is to evaluate the long-term evolution of mild and moderate aortic valve disease in untreated bicuspid valve during supracoronary ascending aortic replacement surgery at our institution.

Enrollment: 75 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients;
• Bicuspid aortic valve;
• Presence of ascending aortic aneurysm in the supra-coronary tract treated with replacement using a prosthetic tube between 2002 and January 2020;
• Untreated aortic valve disease of no more than moderate degree (<2+) at the time of ascending aorta surgery.

Exclusion criteria

• Emergency/urgency procedures;
• Presence of aneurysm extending to the aortic arch or aortic root, with indication for aortic root or aortic arch surgery;
• Tricuspid aortic valve tricuspid;
• Absence of aortic valve disease;
• Presence of moderate-severe or severe aortic valve disease, with indication to a concomitant aortic valve replacement.