Fatigue and Cognitive Dysfunction Due to Synaptopathy or Graft Versus Host (GVH) Disease in the Brain.

Karolinska University Hospital

Status: Enrolling

Conditions: Graft Vs Host Disease; Cognitive Dysfunction; Fatigue

Treatments: Radiation: PET investigation

Study type: Observational

Funder types: Other

Identifiers

NCT07365696

2023-02021-01

Details and patient eligibility

About

Patients undergoing allogenic stem cell transplantation are regularly followed up in the outpatient clinic at Karolinska University Hospital. Here, patients are offered participation the fatigue study measuring both fatigue and cognitive impairment systematically by international standard. Meanwhile liquor samples and advanced PET imaging techniques are available for these patients as part of a research project allowing extensive immunological and radio-morphological studies.

Enrollment: 30 estimated patients

Sex: All

Ages: 20 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: PET images available retrospectively

Trial design

30 participants in 2 patient groups

Patients with fatigue and cognitive dysfunction

Treatment:

Radiation: PET investigation

Patients without fatigue and cognitive dysfunction

Treatment:

Radiation: PET investigation