Fatigue, Sleep Disorders and Endocrine Abnormalities in TBI Patients

Kessler Foundation

Status: Unknown

Conditions: Traumatic Brain Injury

Study type: Observational

Funder types: Other

Identifiers

NCT00775775

R45303

Details and patient eligibility

About

This study will test if patients with moderate to severe traumatic brain injuries also have endocrine abnormalities, examine any existing relationships among fatigue, depression and endocrine abnormalities, and the relationship between endocrine abnormalities, quality of life, and community integration.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having moderate to severe TBI at least 3 months prior to enrollment. This can be demonstrated by a history of loss of consciousness, amnesia or another neurologic deficit after brain injury
• Be between the ages of 18 and 70 years

Exclusion criteria

• History of prior TBI, stroke, seizures, severe psychiatric disturbances (i.e., those known to influence memory performance, such as schizophrenia, bipolar disorder), or drug abuse will be excluded.
• Pregnant, nursing, or planning pregnancy during the study period.
• Dementia
• Other neurological conditions which are associated with aging and known to cause fatigue (e.g. Parkinson's Disease)

Trial design

50 participants in 1 patient group

TBI

Description:

Patients with moderate to severe TBI