Fatty Liver in Long Standing Cholecystectomy (MAFLD-Chole St)

Yasmeen Ahmed Farrag Ahmed

Status: Not yet enrolling

Conditions: Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)-Post-cholecystectomy Metabolic Changes -Hepatic Steatosis

Study type: Observational

Funder types: Other

Identifiers

NCT07284004

Soh-Med--25-11-6MS

Details and patient eligibility

About

This observational study aims to evaluate the association between long-term cholecystectomy and the development of metabolic dysfunction-associated fatty liver disease (MAFLD) in adult patients. The study will assess the prevalence and severity of hepatic steatosis in individuals who underwent cholecystectomy several years earlier and compare clinical, metabolic, and biochemical parameters to identify potential risk factors. The goal is to determine whether cholecystectomy contributes to metabolic alterations that increase the likelihood of MAFLD in the long term.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-

Exclusion criteria

1. Patients less than 18 years old.
2. Body mass index (BMI) ≤ 25 kg/m2
3. Patients with chronic renal failure.
4. Patients with liver cirrhosis.
5. Patients with acute liver dysfunction.
6. Breast feeding and pregnancy.
7. patients have done cholecystectomy less than 5 years ago.

Trial design

100 participants in 1 patient group

Long-term cholecystectomy patients