Feasability, Validty and Reliability of Inertial Sensors

Hasselt University

Status: Completed

Conditions: CVA; Multiple Sclerosis

Treatments: Other: IMUs (Xsens, MVN Studio)

Study type: Interventional

Funder types: Other

Identifiers

NCT03668990

Kinematic01

Details and patient eligibility

About

This study has 3 aimes:

1. To investigate the feasibility of using IMUs (Xsens, MVN Studio) during functional tasks to assess upper limb kinematics in pwMS and stroke survivors. On the one hand, the feasibility of performing the tasks will be investigated . On the other hand, does the XSens give valuable data?
2. To investigate the discriminative validity of kinematic measurements of upper limb movements post-stroke and pwMS in comparison with gender and age-matched healthy controls
3. To investigate the test-retest reliability of the kinematic parameters collected during the different functional tasks in pwMS and stroke survivors

It is a cross-sectional case-controlled observational study, with 3 different groups: 25 Persons with Multiple sclerosis, 25 stroke patients and 50 healthy controls, matched by age and gender.

Enrollment: 18 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Inclusion criteria for all participants: Healthy controls, pwsMS and stroke patients

• No orthopedic or neuro-muscular impairments in the upper limb
• Age > 18 years
• Able to understand and execute the test instructions
• Perceived pain in one of the upper limbs of more than 4/10 (Visual Analog Scale)
• Able to move a joint (wrist, elbow or shoulder) in the upper limb against gravity without resistance (Medical Research Council) (16).

Inclusion criteria for PwMS:

• Diagnosed with MS using McDonald criteria (17)

Inclusion criteria Stroke patients

• First- ever single, unilateral (ischemic or hemorrhagic)
• At least one month after stroke
• No apraxia or hemi spatial neglect

Exclusion criteria

Exclusion Criteria for pwMS only:

• a relapse 3 months before the start of the study
• A change of symptomatic medication during the testing period

Exclusion Criteria:

• People with predominantly ataxia or tremor are excluded from the reliability part of this study

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

18 participants in 3 patient groups

persons with Multiple Sclerosis (MS)

Other group

Description:

25 persons with MS Persons perform funtional-oriented upper limb movments while wearing IMUs (Xsens, MVN Studio). This is a full-body human measurement system based on inertial sensors, biomechanical models and sensor fusion algorithms applied in neurological patients for measuring upper limb movements. Funcitonal-oriented upper limb movements are performed at two different test days.

Treatment:

Other: IMUs (Xsens, MVN Studio)

stroke patients

Other group

Description:

25 stroke patients Persons perform funtional-oriented upper limb movments while wearing IMUs (Xsens, MVN Studio). This is a full-body human measurement system based on inertial sensors, biomechanical models and sensor fusion algorithms applied in neurological patients for measuring upper limb movements. Funcitonal-oriented upper limb movements are performed at two different test days.

Treatment:

Other: IMUs (Xsens, MVN Studio)

Healthy controls

Other group

Description:

50 healthy controls Persons perform funtional-oriented upper limb movments while wearing IMUs (Xsens, MVN Studio). This is a full-body human measurement system based on inertial sensors, biomechanical models and sensor fusion algorithms applied in neurological patients for measuring upper limb movements. Funcitonal-oriented upper limb movements are performed at two different test days.

Treatment:

Other: IMUs (Xsens, MVN Studio)