Feasibility, Acceptability, and Preliminary Efficacy of an HIV Prevention Intervention for Older Black Women

Laneshia Conner

Status: Begins enrollment in 2 months

Conditions: Health Risk Behaviors

Treatments: Behavioral: Adapted W2W; Behavioral: Waitlist Control

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT07181616

K01AG092253-01A1 (U.S. NIH Grant/Contract)

78084

Details and patient eligibility

About

The goal of this clinical trial is to learn whether a group-based HIV prevention program can improve HIV knowledge, prevention behaviors, and testing in older Black women aged 50 and older who live in subsidized housing. The study focuses on improving how HIV prevention programs address the unique needs and life experiences of older Black women.

The main questions it aims to answer are:

Can a revised HIV prevention intervention tailored to reproductive health histories improve HIV knowledge, condom use, and testing in older Black women?

Is the intervention feasible, acceptable, and engaging for participants?

The PI will compare a group of participants receiving the Woman-2-Woman (W2W) intervention to a wait-listed control group to see if the intervention leads to better HIV prevention outcomes.

Participants will:

Join a group-based HIV prevention program designed for older Black women

Be randomly assigned to either:

Start the intervention right away, or

Join a waitlist and start the program 4 weeks later

Take part in four weekly sessions that include group discussions, education, and skill-building activities

Share information about their reproductive health histories and sexual health decisions during focus groups or surveys

Complete questionnaires at the start, after the program ends, and 4 weeks later to assess HIV knowledge, condom use, and testing behavior

This research aims to create a culturally tailored, evidence-based HIV intervention that fits the lives and needs of older Black women and can be used in future, larger studies.

Enrollment: 60 estimated patients

Sex: Female

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• At least 50 years of age
• A resident of Selected sites
• A MOCA score of less than 24
• Self-identifying as an African American woman
• English speaking

Exclusion criteria

• Pre-menopausal
• Cognitive impairment

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Adapted W2W

Experimental group

Description:

HIV intervention focused on aging-related HIV knowledge, identifying HIV prevention practices, and reducing HIV transmission. Intervention given in four, 2 hour educational sessions with a fifth booster session and a final follow up session.

Treatment:

Behavioral: Adapted W2W

Waitlist Control

Active Comparator group

Description:

This group will receive the intervention 8 weeks after the W2W intervention group completes their follow-up and in the same pattern.

Treatment:

Behavioral: Waitlist Control