Feasibility and Reproducibility of T1 Rho MRI in the Evaluation of Hip Cartilage (CARHAT02)

Civil Hospices of Lyon

Status: Completed

Conditions: Healthy Volunteers

Treatments: Device: Hip cartilage MRI

Study type: Interventional

Funder types: Other

Identifiers

NCT02792010

69HCL14_0235

Details and patient eligibility

About

Hip osteoarthritis is a frequent and invalidating disease. Early detection of cartilage modifications could provide better patient treatment. The T1rho MRI sequence allows the quantification of the cartilage signal that is correlated to modifications of the cartilage matrix, notably of the proteoglycans. The primary objective is to evaluate normal values of hip cartilage in vivo using T1rho MRI in healthy subjects and the reproducibility of the measurements. T1rho and T2 mapping sequences were acquired twice during the same session with 30 minutes interval to see if values were modified after a 30 minutes delay in a supine position. The secondary objective was to assess the correlation between T1rho and T2 values.

Enrollment: 31 patients

Sex: All

Ages: 18 to 49 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI <30
• Accepting to participate in the study and signed the written informed consent
• Covered by a health insurance system

Exclusion criteria

• Pregnant woman or risk of pregnancy
• MRI contraindication
• Protected adults
• Language barrier
• Previous or current hip pain

Trial design

31 participants in 1 patient group

T1rho MRI

Experimental group

Description:

Patients included had hip cartilage MRI with acquisition of T1rho MRI sequence.

Treatment:

Device: Hip cartilage MRI