Feasibility Neurocognitive Outcome After Transplant

Stanford University

Status

Active, not recruiting

Conditions

Stem Cell Transplantation

Acute Lymphoblastic Leukemia

Pediatric Cancer

Treatments

Behavioral: Cognitive rehabilitation program

Study type

Interventional

Funder types

Other

Identifiers

NCT02300961

NCI-2014-02434 (Other Identifier)

IRB-31680

Details and patient eligibility

About

This pilot study will primarily be evaluated by feasibility and adherence to an iPad-based neurocognitive intervention program. It will secondarily be evaluated by performance on the neurocognitive testing post-transplant and change in performance in subsequent years.

Enrollment

17 patients

Sex

All

Ages

6 to 21 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All patients must have a histologic or cytological diagnosis of ALL treated with stem cell transplantation. There are no restrictions on prior therapy.
Patients must be between the ages of 6 years and 21 years of age (inclusive), but there will be no discrimination based on gender, race, creed, or ethnic background. The age limits are set at 6 years of age in order to ensure that patients will be able to participate in these specific cognitive rehabilitation tasks. ECOG/KPS will not be employed.
Patient and/or parents/guardians as appropriate must sign an informed consent, be mentally responsible, able to understand and willing to sign a written informed consent.

Exclusion criteria

Subjects with significant concurrent medical complications that in the judgment of the Principal Investigator(s) could affect the patient's ability to complete the planned trial. There are no therapy restrictions or restrictions regarding the use of other Investigational Agents.
Pregnant patients will be excluded.