Feasibility of a Cytokine Expression Profile in Immune Cells as an Orientation Tool in Therapeutic Decisions for Auto-inflammatory and Auto-immune Diseases (IL-MAI)

Centre Hospitalier Universitaire de Nīmes

Status: Completed

Conditions: Rheumatoid Arthritis

Treatments: Procedure: Blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT03280797

LOCAL/2016/TAT01

Details and patient eligibility

About

This study will assess the feasibility of using cytokine expression profiles in blood samples as a method for evaluating rheumatoid polyarthritis

Enrollment: 44 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The patient must have given their free and informed consent and signed the consent form
• The patient must be a member or beneficiary of a health insurance plan
• Patient is at least 18 years old
• Subjects included as patients have rheumatoid polyarthritis according to ACR EULA 2010, DAS28>3.2 criteria
• Subjects included as controls are healthy volunteers who have no overexpression of cytokines

Exclusion criteria

• The subject is participating in an interventional study, or is in a period of exclusion determined by a previous study
• The subject refuses to sign the consent
• It is impossible to give the subject informed information
• The patient has had at least 3 months of specific treatment that can potentially impact cytokine profile

Trial design

Primary purpose: Screening

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 2 patient groups

Control

Other group

Treatment:

Procedure: Blood sample

Rheumatoid arthritis patients

Other group

Treatment:

Procedure: Blood sample