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Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures

P

Pathfinder Therapeutics

Status

Terminated

Conditions

Liver Cancer

Study type

Observational

Funder types

Industry

Identifiers

NCT01238653
PTI-LC-2009-02

Details and patient eligibility

About

This study was designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic liver procedure. The hypothesis is that there will be no clinically relevant difference between the error measurements obtained during the laparoscopic procedures in this study when compared with those obtained during previous open liver registration studies.

The surface of the liver will be manually swabbed with the study tracked laparoscopic probe with landmarks noted during data collection. After registration of the liver is obtained, the registration points obtained during this procedure will be evaluated by the surgeon by moving the tracked laparoscopic probe over the liver surface and evaluating the location of the tracked laparoscopic probe displayed on the guidance system three dimensional (3D) image. The surgeon will accept or reject the registration accuracy.

Full description

The Pathfinder System used during this study is used for data collection purposes only and is not used during the surgical procedure as an image guided system.

Preoperative computed tomography (CT) scans, obtained as standard of care, will be used to generate the image guided liver system 3D liver surface images used during the study.

During the laparoscopic procedure, the Pathfinder device will be inserted through the standard laparoscopic ports (5mm or 10mm) being used for the staging procedure.

A total study population will include 20 subjects that complete the laparoscopic procedure scheduled.

Enrollment

8 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Scheduled for laparoscopic procedure
  • Had a preoperative CT image that includes the liver

Exclusion criteria

  • Severe cirrhosis of the liver
  • Kidney failure or dialysis
  • Unable to consent

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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