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Feasibility of ERAS Protocol in T4 Colorectal Cancer Patients

U

University of Rome Tor Vergata

Status

Completed

Conditions

ERAS
T4 Colorectal Cancer
Colon Cancer
Fast Track Protocol

Treatments

Behavioral: ERAS protocol

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Patients diagnosed with T4 colorectal cancer represent a specific subgroup of colorectal patients, frequently composed of fragile patients whose advanced nature of the disease often requires a multi organ resection by an open surgery approach and frequently leads to higher intra/postoperative complication.Those characteristics makes them to be considered less suitable for ERAS protocol, especially regarding an expected difficult compliance to postoperative items.

The impact of enhanced recovery program on postoperative outcomes in this subset of patients has never been addressed in literature, in fact most of studies either excluded T4 patients due to higher rates of complication or adopted an homogeneous patient sampling analizing all stage colorectal cancer together.

Our aim is to investigate the feasibility of ERAS protocol in T4 colorectal patient, primary outcome was to compare postoperative lenght of stay between T4 colorectal patients treated with ERAS protcol and those treated with standard of care.

Enrollment

82 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • colorectal cacer
  • hystologic diagnosis of adenocarcinoma of the colon/rectum
  • clinically staged T4
  • written informed consent to surgery obtained

Exclusion criteria

  • pregnancy
  • failure to perform colonic or rectal resection
  • synchronous cancer at time of colorectal cancer diagnosis

Trial design

82 participants in 2 patient groups

t4 colorectal cancer treated with ERAS protocol
Description:
prospective from January 2016 to May 2020
Treatment:
Behavioral: ERAS protocol
t4 colorectal cancer treated with standards of care
Description:
retrospective from January 2010 to December 2015

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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