Feasibility of Pulsed Field Ablation Under Mild Conscious Sedation

Liverpool Heart and Chest Hospital NHS Foundation Trust

Status: Completed

Conditions: Atrial Fibrillation

Treatments: Procedure: Catheter ablation

Study type: Observational

Funder types: Other

Identifiers

NCT06014814

IRAS (Other Identifier)

PFA-Sedation-Study

Details and patient eligibility

About

Prospective case-control study comparing pulsed field ablation for atrial fibrillation under mild conscious sedation vs standard of care (general anaesthesia).

Full description

This study will prospectively assess 40 patients (20 per arm). Those in the general anaesthesia arm will undergo routine clinical practice. Those in the mild conscious sedation arm will undergo pulsed field ablation with intravenous sedation but without general anaesthesia, though conversion to general anaesthesia is allowed if the patient does not tolerate the procedure.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients clinically referred for and undergoing catheter ablation of atrial fibrillation using pulsed field ablation

Exclusion criteria

• Inability to provide informed consent

Trial design

40 participants in 2 patient groups

Pulsed Field Ablation - General Anaesthesia

Description:

Patients undergoing pulsed field ablation for atrial fibrillation under general anaesthetic.

Treatment:

Procedure: Catheter ablation

Pulsed Field Ablation - Mild Conscious Sedation

Description:

Patients undergoing pulsed field ablation for atrial fibrillation under mild conscious sedation.

Treatment:

Procedure: Catheter ablation