Feasibility of Saliva and Remote Monitoring of Active Cytomegalovirus (CMV) Infection and Symptoms During Ovarian Cancer Treatment

Mayo Clinic

Status: Enrolling

Conditions: Cytomegaloviral Infection; Cancer-related Cognitive Dysfunction; Primary Peritoneal Carcinoma; Ovarian Carcinoma; Fallopian Tube Carcinoma

Treatments: Other: Non-Interventional Study

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT06870539

24-011332 (Other Identifier)

P50CA136393 (U.S. NIH Grant/Contract)

NCI-2025-01230 (Registry Identifier)

Details and patient eligibility

About

This study evaluates the feasibility and accuracy of using saliva to remotely monitor cytomegalovirus (CMV) infection in individuals receiving treatment for ovarian cancer.

Enrollment: 28 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18
• Ability to read and write in English
• Diagnosed with ovarian cancer (ovarian, primary peritoneal, fallopian tube)
• Receiving care from providers at Mayo Clinic
• Regardless of diseases status, actively receiving treatment for ovarian cancer (frontline, maintenance, progression, recurrence)

Exclusion criteria

• Pregnant at the time of study participation
• Inability to provide informed written consent
• History of dementia, stroke, brain tumors or other condition which may impair cognitive functioning

Trial design

28 participants in 1 patient group

Observational

Description:

Patients undergo saliva sample collection as well as in-clinic or at-home blood sample collection on study. Patients also complete questionnaires, undergo cognitive function testing, and have their medical records reviewed on study.

Treatment:

Other: Non-Interventional Study