Feasibility Study of Vessel Analysis for Noninvasive Diagnosis of Malignancy in Breast Tumors

University of North Carolina (UNC)

Status: Terminated

Conditions: Breast Cancer

Treatments: Other: Magnetic Resonance Angiography (MRA) of the Breast

Study type: Interventional

Funder types: Other

Identifiers

NCT00630292

LCCC0718

Details and patient eligibility

About

This is a pilot study designed to explore the feasibility of non-invasively diagnosing the presence of cancer in the breast using non-invasive magnetic resonance imaging (MRI) methods and an analysis of vessel shape defined from these magnetic resonance images.

Enrollment: 6 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult women (age >= 18),
• with Histologically documented newly diagnosed stage II-IV invasive breast cancer appropriate for neoadjuvant (preoperative) systemic therapy.
• ECOG performance status of 0, 1, or 2 at the initiation of the study.

Exclusion criteria

• pregnant women
• women with contralateral mastectomies
• known bilateral tumors
• subjects prone to claustrophobia
• contraindicated to have MRI
• mentally impaired
• not fluent in english

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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6 participants in 1 patient group

1

Experimental group

Treatment:

Other: Magnetic Resonance Angiography (MRA) of the Breast