Feasibility Trial Using an Inpatient Insulin Dosing Calculator

University of Washington

Status

Completed

Conditions

Diabetes Mellitus, Type 2

Treatments

Other: Initial insulin dosing using the calculator

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT06206525

STUDY00018906

2T32DK007247-41 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are:

Whether using this calculator leads to no excessive hypoglycemia?
Whether using this calculator leads to a decrease of hyperglycemia?

Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.

Enrollment

38 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients who are admitted to University of Washington Medical Centers
With history of type 2 and/or steroid-induced diabetes mellitus
Receiving insulin therapy prior to admission

Exclusion criteria

Patients who are admitted to ICU or obstetrics ward
Patients who are admitted for elective surgery or procedure
Patients who present with diabetic ketone acidosis, hyperosmolar hyperglycemic state or require intravenous insulin infusion
Patients who have no meal intake for 24 hours prior to admission, or planned nothing per oral (NPO) during the first 24 hours after admission
Patients who report low appetite (25% or less) on admission or have a significantly decreased level of consciousness that they unlikely eat right after admission
Patients who receive enteral feeding after admission
Patients who develop severe acute kidney injury needing dialysis therapy