Features Emotional Responses in Adults With Autism: Comparison With Bipolar Disorder (REMBAU)

Regional University Hospital Center (CHRU)

Status

Unknown

Conditions

Autism Spectrum Disorder

Bipolar Disorder

Study type

Observational

Funder types

Other

Identifiers

NCT02423499

2014-A00431-46 (Other Identifier)

PHAO13-ML/REMBAU

Details and patient eligibility

About

The objective of this study is to identify the specific characteristics of Autism Spectrum Disorder (ASD) in emotional response profiles and shared with Bipolar Disorder (BD) characteristics.

Enrollment

90 estimated patients

Sex

All

Ages

18 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

For all participants:
- Age between 18 and 50 years
- Normal vision (or corrected)
- Absence of neurological disorder (epilepsy , head trauma, ... )
- Ability to understand information about the protocol
- Informed and signed consent
- normal mood (euthymia)
- normal or high intelligence
Subjects with ASD:
- Subjects with an autism spectrum disorder according to the DSM-5
- The diagnosis is confirmed by diagnostic interviews: ADI- R (Autism Diagnostic Interview-Revised) and / or ADOS (Autism Diagnostic Observation Schedule ) .
Subjects with bipolar disorder:
- Diagnosis of bipolar disorder according to DSM-IV-TR or DSM -5
- The diagnosis is confirmed by the MINI 6.0 (The Mini-International Neuropsychiatric Interview) .
Healthy volunteers:
- Inclusion after checking the national register of healthy volunteers
- No history of disease of the central nervous system or psychiatric disorder
- No family history of ASD or BD in the first degree
- Lack of psychotropic medication or current cardiotropic
- Lack of psychiatric disorder on Axis I MINI 6.0
- AQ Score < 32