Fecal Calprotectin in Patients Infected with Intestinal Protozoan Infections

Sohag University

Status: Not yet enrolling

Conditions: Fecal Calprotectin in Intestinal Protozoa

Study type: Observational

Funder types: Other

Identifiers

NCT06890455

Soh-Med--25-3-07MS

Details and patient eligibility

About

Calprotectin extracted from stool can be detected easily using ELISA. Numerous studies have shown that fecal calprotectin concentrations demonstrate a good correlation with intestinal inflammation This study aims to detect the relationship between fecal calprotectin and Blastocystis hominis and Entamoeba histolytica infections.

Enrollment: 120 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

120 fecal samples will be collected as the following:

• 40 samples from patients complaining of gastrointestinal manifestations and only infected with B.hominis and E.histolytica.
• 40 samples from patients complaining of gastrointestinal manifestations without any protozoal infection.
• 40 healthy control cross-matched volunteers (without gastrointestinal manifestations, or intestinal parasites).

Exclusion criteria

• persons received antiparasitic drugs or antibiotic 2 weeks before sample collection Patients with mixed intestinal protozoa Patients with intestinal protozoa rather than Entamoeba histolytica and Blastocystis

Trial design

120 participants in 3 patient groups

Case group

Description:

40 patients complaining of gastrointestinal manifestations and infected with Blastocystis or Entamoeba histolytica

Control group 1

Description:

40 persons complaining of gastrointestinal manifestations without any protozoal infections

Control group 2

Description:

- 40 healthy control cross-matched volunteers (without gastrointestinal manifestations, or intestinal parasites).