Feeding Premature Infants During Non-invasive Respiratory Support

Rambam Health Care Campus

Status: Unknown

Conditions: Premature Infant; Non-invasive Respiratory Support

Treatments: Other: Length of feeding

Study type: Interventional

Funder types: Other

Identifiers

NCT03852641

Feeding on NIPPV

Details and patient eligibility

About

A randomized control trial comparing bolus gavage feeds to continuous feed among premature infants supported by non-invasive respiratory support

Enrollment: 100 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infants <1500gr, on non-invasive respiratory support
• Feeding>20 ml/kg/day

Exclusion criteria

• Major congenital malformations
• Unstable infants because of sepsis, central nervous system, cardiac or other significant morbidities
• Gastrointestinal morbidity such as spontaneous intestinal perforation (SIP) and necrotising enterocolitis (NEC).

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

100 participants in 2 patient groups

Bolus gavage feeds

Experimental group

Description:

Bolus gavage feeds over 15-30 minutes

Treatment:

Other: Length of feeding

Continuous feeds

Experimental group

Description:

Continuous feeds over 2.0 hrs

Treatment:

Other: Length of feeding