Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR)

Hopital de l'Enfant-Jesus

Status and phase: Completed; Phase 2; Phase 1

Conditions: Total Knee Replacement

Treatments: Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT00910013

PEJ-340

Details and patient eligibility

About

Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.

The purpose of the study is to compare if the adjunction of intra-articular ropivacaine to a femoral block is more effective on narcotics consumption than the block alone after TKR.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary total knee replacement
• Age > 18 years old
• Accept the study

Exclusion criteria

• Revision surgery
• Use of anticoagulants drugs
• Neurologic disorder
• Unable to sign consent form

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 1 patient group

Ropivacaine + femoral block

Experimental group

Description:

After the surgery is proceeded and after the closure of the joint capsule, 20 cc of ropivacaine 0.5% is inserted intra-articular through a catheter.

Treatment:

Drug: Ropivacaine