Femoral Cartilage Thickness in Knee Osteoarthritis

Kanuni Sultan Suleyman Training and Research Hospital

Status: Enrolling

Conditions: Knee Osteoarthritis

Treatments: Diagnostic Test: ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality

Study type: Observational

Funder types: Other

Identifiers

NCT05456711

KAEK/2022.05.103

Details and patient eligibility

About

The aim of the study to investigate the relationship between femoral cartilage thickness in Ultrasonographic evaluation and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis

Full description

Aim: The aim of the study is to investigate the relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in participants with Knee Osteoarthritis.

Methods: This study is designed as a prospective, cross-sectional trial. 90 participants aged between 50-65 years with knee osteoarthritis(OA) and at least 50 participants without any symptom for knee OA are included in the study in accordance with the inclusion criteria. Participants' demographic characteristics will be evaluated, and ultrasonographic measurement will be performed for measuring femoral cartilage thickness. Visual Analog scale will be used for pain severity and Western Ontario and McMaster Universities Osteoartrit index (WOMAC) will be used for assessing functionality of the patients. Also hematologic parameters(neutrophils, leucocytes, lymphocytes, platelet, CRP, erythrocyte sedimentation rate) will be evaluated for investigating the inflammation. The relationship between femoral cartilage thickness and inflammatory parameters, pain severity and functionality in knee osteoarthritis will be analysed for both group.

Enrollment: 140 estimated patients

Sex: All

Ages: 50 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosed as knee osteoarthritis
• aged between 50-65 years
• volunteer to participate in the study

Exclusion criteria

• limitation of cooperation
• moderate to severe dementia or mental retardation, which may cause limitations in examination, testing and treatment
• refusal to participate in the study
• pprevious total knee prosthesis surgery
• secondary osteoarthritis

Trial design

140 participants in 2 patient groups

knee osteoarthritis

Description:

ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality

Treatment:

Diagnostic Test: ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality

healthy control

Description:

ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality

Treatment:

Diagnostic Test: ultrasonographic measurement for femoral cartilage thickness VAS for pain severity WOMAC for functionality