Fentanyl Test in Children's Adenotonsillectomy

Fudan University

Status: Completed

Conditions: Obstructive Sleep Apnea

Treatments: Drug: Fentanyl

Study type: Observational

Funder types: Other

Identifiers

NCT02484222

FTCA-01

Details and patient eligibility

About

The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested dosage of morphine postoperatively.

Full description

All the patients were intubated. Sevoflurane was used for maintenance without any opioids. Before the end of the procedure, spontaneous respiratory was recovered. All the patients were given 1 mcg/kg fentanyl i.v. after the end of the procedure. The positive result was defined as spontaneous respiratory rate decreased more than 50%, the others were defined as negative result. All the patients were given morphine for pain relief according to our protocol after extubation.

Enrollment: 80 patients

Sex: All

Ages: 3 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:meet all of the following

1. the American society of anesthesiologists (ASA) class Ⅰ ~ Ⅱ
2. the age of 3 ~ 7 years old
3. children who underwent selective adenotonsillectomy.

Exclusion Criteria:meet anyone of the following

1. craniofacial malformations
2. mental retardation
3. BMI > 22 kg/m2
4. a history of bronchial asthma
5. a recent history of opioid use.