ClinicalTrials.Veeva

Menu

Fenugreek: an Emergent Allergen

P

Paola Miciullo

Status

Completed

Conditions

Fenugreek Hypersensitivity - Cross-reactivity - Food Allergy

Treatments

Diagnostic Test: Skin prick test

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

Fenugreek or Trigonella foenum greacum is an ancient medicinal plant native to the eastern Mediterranean, later spread to Asia (especially in India); it belongs to Rosaceae order, Leguminosae family, subfamily of Papilonaceae and it is used as a medicinal herb, spice or food. It is a component of spice mix, such as curry, and it is also used as a supplement in wheat and corn flour for bread-making. Fenugreek appears to have many health benefits and potential medicinal properties (antioxidant, antidiabetic, hepatoprotective, hypocholesterolemic, antimicrobial, anti-inflammatory, neuroprotective, anticarcinogenic, antiulcer, and antilithigenic) both in vitro and in vivo studies; for this reason it may be increasingly being used as nutraceutical formulations (powder, herbal teas, tablets and various combinations).This study aims to describe patients who came to our operating unit for suspected adverse reaction after ingestion of fenugreek and to highlight possible cross-reactivity between fenugreek and other legumes or other foods. Given the increasing use of novel spices in Mediterranean cuisine and the possible spread of fenugreek-based nutraceuticals, it is relevant to draw attention to possible allergic reactions.

Enrollment

15 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • age > 18 yo
  • history of allergic reactions to spices
  • history of allergic reactions to phytotherapics containing fenugreek

Exclusion criteria

  • age < 18 yo
  • non suggestive history of allergic reactions to spices

Trial design

15 participants in 2 patient groups

Allergic patients to fenugreek
Treatment:
Diagnostic Test: Skin prick test
Non allergic patients to fenugreek
Treatment:
Diagnostic Test: Skin prick test

Trial documents
2

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems