Fenugreek Wraps in Osteoarthritis of the Knee (BoGon)

Universität Duisburg-Essen

Status: Completed

Conditions: Osteoarthritis, Knee

Treatments: Other: Fenugreek wrap; Drug: Diclofenac Gel

Study type: Interventional

Funder types: Other

Identifiers

NCT03528824

BoGon

Details and patient eligibility

About

This randomised controlled trial aims to investigate the efficacy of fenugreek wraps in the treatment of primary symptomatic osteoarthritis of the knee. 81 patients will be randomised into one of 3 groups and apply fenugreek wraps or diclofenac gel daily for 4 weeks or receive only usual care. Efficacy will be measured using questionnaire on pain, disability,function, quality of life and pressure pain sensitivity.

Enrollment: 81 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteoarthritis of the knee, Kellgren Lawrence stadium 2-3
• at least 50% of days with complaints in past 3 months
• initial pain intensity >45mm on a 100mm visual analoge scale

Exclusion criteria

• systemic medication with corticoids or immunosuppressive drugs
• systemic medication with chondroitinsulfate or glucosamine
• secondary arthrosis
• operation on the knee within the past 12 months
• injection within 4 weeks (cortisone) or 6 months prior (hyaluronic acid)
• severe comorbidities (tumor, psychiatric disorders etc.)
• participation in other studies, regarding gonarthrosis
• asthma
• pregnancy, breastfeeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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81 participants in 3 patient groups

Fenugreek wraps

Experimental group

Description:

Daily application of fenugreek wraps for 1/2-2 hours per day, 4 weeks application

Treatment:

Other: Fenugreek wrap

Diclofenac gel

Active Comparator group

Description:

Daily application of diclofenac gel, 4 weeks application

Treatment:

Drug: Diclofenac Gel

Usual care

No Intervention group

Description:

no specific intervention