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Fertility After Transvaginal Surgery or Uterine Artery Embolization Combined With Uterine Curettage in Patients With Cesarean Scar Pregnancy

S

Shanghai First Maternity and Infant Hospital

Status

Unknown

Conditions

Menstruation
Ovarian Function
Magnetic Resonance Imaging

Treatments

Procedure: transvaginal surgery;UAE and D&C

Study type

Interventional

Funder types

Other

Identifiers

NCT02933190
ShanghaiFMIH-CSP

Details and patient eligibility

About

To investigate the fertility in patients after treatment by transvaginal surgery or uterine artery embolization combined with uterine curettage

Enrollment

50 estimated patients

Sex

Female

Volunteers

No Healthy Volunteers

Inclusion criteria

  • increased levels of serum β-hCG and ultrasonography findings. The criteria for diagnosis by ultrasonography was the presence of the following: (1) an empty uterine cavity and endocervical canal; (2) detection of the placenta and/or a gestational sac embedded in the hysterectomy scar; (3) the presence of the gestation sac with or without a fetal pole and with or without fetal cardiac activity (depending on the gestational age) in the anterior part of the uterine isthmus; and (4) a thin (1-3 mm) or absent myometrial layer between the gestational sac and the bladder(24). All patients had taken Magnetic Resonance Imaging (MRI) to clarify the diagnosis . Pregnancy tissues were identified by histopathology examinations of the surgical tissues.

Exclusion criteria

  • All enrolled patients had no contraindications for transvaginal surgery or UAE, including renal failure, active pelvic infection, clotting disorders, or known allergy to the contrast material.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Single Group Assignment

Masking

Triple Blind

50 participants in 1 patient group

CSP;transvaginal surgery;UAE and D&C
Other group
Description:
Cesarean scar pregnancy (CSP) refers to the implantation of a gestational sac with the myometrium at the site of a previous cesarean scar
Treatment:
Procedure: transvaginal surgery;UAE and D&C

Trial contacts and locations

1

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Central trial contact

Xipeng Wang; Huihui Chen

Data sourced from clinicaltrials.gov

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