Fetal Cardiac Effects of Tocolytic Nifedipine and Magnesium Sulfate

Sanliurfa Education and Research Hospital

Status: Active, not recruiting

Conditions: Unexpected Fetal Cardiac Effects of Nifedipine and MgSO4

Study type: Observational

Funder types: Other

Identifiers

NCT06904534

SEAH-CARD

Details and patient eligibility

About

The potential unexpected effects of nifedipine and MgSO4, the tocolytic agents used for the indication of preterm labor, on fetal heart will be determined. In this study, the fetal echocardiographic findings of nifedipine and MgSO4 will be compared.

Full description

This study will include pregnancies at 24-34 weeks of gestation that are using nifedipine and MgSO4 for tocolysis. Fetal echocardiographic findings of these pregnancies will be recorded

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:-Patients with preterm labor indication at 24-34 weeks of gestation

-Treated with nifedipine or MgSO4 for tocolysis

Exclusion Criteria:

• Multiple pregnancy
• premature rupture of membranes
• Chorioamnionitis
• Placental abruption
• Severe fetal growth restriction
• Congenital anomalies of the fetus
• Preeclampsia
• Oligohydramnios
• Maternal diabetes
• Contraindications for the use of nifedipine and/or MgSO4 in the mother

Trial design

100 participants in 1 patient group

Pregnancies using nifedipine and MgSO4 for tocolytic purposes