Fetal Parenchymatic Evaluation (Liver, Spleen) Using T2* Sequences

Sheba Medical Center

Status: Unknown

Conditions: Iron Overload

Study type: Observational

Funder types: Other

Identifiers

NCT01121094

SHEBA-09-7502-OG-SMC

Details and patient eligibility

About

The purpose of this study is to prospectively evaluated the T2* values of normal feti.A standardized scale of T2* values for fetal and neonatal iron organ overload have yet to be reported or devised.

Full description

The purpose of this study is to prospectively evaluate the T2* values of normal feti. This study will be offered to mothers undergoing fetal MRI for any indication. Subjects will be required to sign an informed consent from. The addition of T2* sequences will add 2-4 minutes to the whole scan, not exposing the mother or the fetus to ionizing radiation or the administration of contrast material. A standardized scale has been created and multi-center studies have been conducted using different vendor scanners in order to verify the consistency of these scale. T2 and T2* sequences have been addressed anecdotally in the literature as non invasive options for the evaluation fetal iron deposition . However, a standardized scale of T2* values for fetal and neonatal iron organ overload have yet to be reported or devised.

Enrollment: 50 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Any MRI study for fetus

Exclusion criteria

• Known iron deposition problem in the mother of fetus