Fever Tracking Study

University Hospital Basel

Status: Completed

Conditions: Immune Response to mRNA COVID-19 Vaccination; Core Body Temperature in Healthy Subjects

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT05475067

Fever Tracking

Details and patient eligibility

About

The aim of this study is to investigate the feasibility of continuous fever tracking of participants having fever symptoms in a home setting, using a core body temperature (CBT) sensor. CBT as measured by the wearable sensors will be coampared with CBT as measured by ingestible electronc pills (reference).

A secondary research question is, if the CBT behavior of the the participants in a home setting can be compared to previously described CBT profiles in the literature, and if special patterns can be identified.

Enrollment: 61 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18-60 years old
• Informed consent signed
• Either:

Acute fever symptoms at inclusion (at least 38.0°C) and Test for COVID-19 at the day of inclusion

• Or: Second shot or booster of mRNA COVD-19 vaccination (Comirnaty® or COVID-19 Vaccine Moderna®) at day of inclusion

Exclusion criteria

• Any participant who, for any reason, is unable to independently consent to participate in the study and/or who is unable to independently follow the study protocol.

• Any participant with previous surgical procedures in the gastrointestinal tract

• Inability to swallow pills

• Any participant of ≤40 kg body weight

• A scheduled MRI examination in the period from the start of the measurements until seven days after ingestion of the electronic pill.

• Any participant being pregnant

• Impairment or disability of the upper extremity likely to have a negative impact on the quality of measurements:

  • Wounds
  • Active venous access
  • Amputations
  • Dialysis shunt
  • Edema
  • Axillary dissection
  • Continuous long-term monitoring of blood pressure
  • Tattoos

• Known allergy to plastics / latex

• Language problems