Fiber Fermentation Study

University of Hohenheim

Status

Completed

Conditions

Intestinal Health

Treatments

Dietary Supplement: Dietary fiber supplementation

Study type

Interventional

Funder types

Other

Identifiers

NCT04570137

FiberStudy

Details and patient eligibility

About

The aim of the study is to better understand the interplay between the intake of dietary fiber and intestinal bacteria, their metabolic activity and the effect on the intestinal barrier.

The effect of two different dietary fiber supplements is tested (arabinoxylan & ß-glucan versus inulin & fructooligosaccharides) in a randomized crossover intervention trial including healthy volunteers.

Enrollment

21 patients

Sex

All

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

18 to 65 years
signed written informed consent
willingness not to change the dietary pattern in the course of the study

Exclusion criteria

BMI below 18 or above 30
acute or chronic gastrointestinal symptoms
neoplastic diseases
very strict diets, including raw foodists and frutarians
regular smoking (more than one box per day)
intake of antibiotics, immunosuppressants, or any intestinal therapeutics three months prior to study begin
supplementation of fibers three months prior to study begin
simultaneous participation in another clinical study
pregnancy / breastfeeding
relevant violations of the study protocol
intolerance to the fiber supplements (including wheat, oat, chicory)
occurrence of relevant diseases (individual decision by study physicians)
revocation of consent
placement in a clinic or similar facility based on an official or court order