Fibrin Glue Versus Titanium Platelet-rich Fibrin in Lateral Sinus Lifting

Hams Hamed Abdelrahman

Status: Completed

Conditions: Sinus Floor Augmentation; Graftless Sinus Elevation

Treatments: Other: Negative control; Other: T-PRF; Other: Fibrin Glue

Study type: Interventional

Funder types: Other

Identifiers

NCT05831267

Sinus_lifting_2022

Details and patient eligibility

About

Graftless sinus lift with simultaneous implant placement is one of the new techniques, this new technique is presented based on the physiology of intrasinus bone repair.

Schneiderian membrane is known to have an osteogenic nature, now blood clot can be considered autologous osteogenic graft material, to which osteoprogenitors can migrate, differentiate, and regenerate bone.

The aim of this study is to evaluate the effectiveness of using Fibrin glue versus Titanium platelet rich fibrin (T-PRF) as a sole filling material in lateral sinus lifting using with simultaneous implant placement in comparison to a negative control group.

Enrollment: 30 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients requiring implant placement in the posterior maxilla.
• Tooth extractions at the implant sites were performed at least 4 months before surgery.
• Residual bone height between the alveolar bone crest and the sinus floor is 3-5 mm

Exclusion criteria

• Maxillary sinus pathologies (sinusitis, long-standing nasal obstruction).
• Any disease-contraindicating surgery (e.g. uncontrolled diabetes).
• Heavy smokers (smoke greater than or equal 25 cigarettes daily).
• Acute oral infections.
• Untreated periodontal disease (gingival index 2 and 3).
• Poor oral hygiene ( Silness-Löe index (score 2-3) ).
• A history of radiotherapy or chemotherapy of the head and neck region.
• Pregnancy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 3 patient groups

Study group 1

Experimental group

Treatment:

Other: Fibrin Glue

Study group 2

Experimental group

Treatment:

Other: T-PRF

Control group

Other group

Treatment:

Other: Negative control