Fibrinogen to Albumin Ratio and C-reactive Protein to Albumin Ratio in Juvenile Idiopathic Arthritis

Assiut University

Status: Not yet enrolling

Conditions: Juvenile Idiopathic Arthritis

Treatments: Diagnostic Test: fibrinogen to albumin ratio (AFR) and C-reactive protein to albumin ratio (CAR)

Study type: Observational

Funder types: Other

Identifiers

NCT06024486

Juvenile arthritis assiut u

Details and patient eligibility

About

The fibrinogen to albumin ratio (FAR) and C-reactive protein to albumin ratio (CAR) have emerged as useful biomarkers to predict systemic inflammation. The aim here is to investigate the relation between FAR/CAR and Juvenile arthritis disease activity score (JASDAS27) in Juvenile idiopathic arthritis (JIA)

Full description

The JADAS27 includes a selected count of the following joints: cervical spine, elbows, wrists, metacarpophalangeal joints (from first to third), proximal interphalangeal joints, hips, knees and ankles.

Enrollment: 50 estimated patients

Sex: All

Ages: Under 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All juvenile idiopathic arthritis fulfilling the criteria of International League of Associations for Rheumatology (ILAR) and age and sex matched healthy subjects

Exclusion criteria

• Other systemic inflammatory or autoimmune disorders.
• History of corticosteroid medication in the last 6 months.
• Liver diseases.
• Malignancy.

Trial design

50 participants in 2 patient groups

JIA cases

Description:

juvenile idiopathic arthritis cases

Treatment:

Diagnostic Test: fibrinogen to albumin ratio (AFR) and C-reactive protein to albumin ratio (CAR)

CONTROL

Description:

age and sex matched healthy controls

Treatment:

Diagnostic Test: fibrinogen to albumin ratio (AFR) and C-reactive protein to albumin ratio (CAR)