Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities

The Mentor Initiative

Status and phase: Completed; Phase 3

Conditions: Vector Borne Diseases; Malaria; Childhood ALL

Treatments: Diagnostic Test: test and treat malaria cases; Behavioral: Information and Education Campaigns (IEC); Combination Product: Mesh - spatial repellent impregnated with transfluthrin (2500mg)

Study type: Interventional

Funder types: Other

Identifiers

NCT06179732

USDA01YEM - Nigeria

Details and patient eligibility

About

The aim of this study is to determine the effectiveness of a new spatial repellent (called Mesh) at repelling multiple disease vectors and, reducing clinical malaria rates in temporary shelters and camp settings. The design of the study will be a two-armed cluster randomised trial.

By conducting the research in challenging camp settings in the north of Nigeria, the MENTOR Initiative aims to determine whether Mesh can be effective in harsh camp conditions where communities are living in conflict area temporary shelters.

Enrollment: 2,400 patients

Sex: All

Ages: 6 to 10 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Shelters with 1 or more children from 6-10 years old
• Shelters with an adult/head of the household

Exclusion criteria

• Shelters without children from 6-10 years old

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2,400 participants in 2 patient groups

Control

No Intervention group

Description:

1. Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home). 2. Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age

Mesh

Experimental group

Description:

1. Information and Education Campaigns (IEC) campaigns will formally encourage breeding site management through; good practice household-level water storage (covering and cleaning of water storage containers) and waste management (removal of potential breeding sites in and around the home). 2. Epidemiological surveillance: test and treat malaria cases in children 6 - 10 years of age 3. Mesh product distributed to households

Treatment:

Behavioral: Information and Education Campaigns (IEC)

Combination Product: Mesh - spatial repellent impregnated with transfluthrin (2500mg)

Diagnostic Test: test and treat malaria cases