Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD

University of Illinois

Status: Enrolling

Conditions: End Stage Renal Disease on Dialysis

Treatments: Behavioral: Fight Fatigue; Other: Attention Control

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT07014111

R34AT012770 (U.S. NIH Grant/Contract)

STUDY2025-0281

Details and patient eligibility

About

Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of ESKD diagnosis and receiving hemodialysis for at least 3 months
• Can read and speak English
• Fatigue measured via visual analogue scale, score ≥4 over the last week
• Able to stand and walk one block
• Has a cell phone that can receive text messages

Exclusion criteria

• Patient's nephrologist refuses for them to participate
• Unstable angina
• Unstable pulmonary disease or pulmonary symptoms that preclude participation
• Lower-extremity amputation without prosthetic (BKA, AKA) -Orthopedic or neurologic condition that would preclude walking or tensing/releasing of muscles-
• Cognitive impairment that, in the judgement of the research team, precludes trial participation
• Participation in the formative phase of the development of Fight Fatigue

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Fight Fatigue

Experimental group

Description:

Combined progressive muscle relaxation and walking (increasing step count) 12-week intervention that consists of education/training followed by text messages

Treatment:

Behavioral: Fight Fatigue

Attention Control

Active Comparator group

Description:

End-stage kidney disease education, followed by text messages (over 12 weeks)

Treatment:

Other: Attention Control