Financial Incentives and Recruitment to the APT Webstudy (FIND-AD)

University of Southern California

Status: Enrolling

Conditions: Prodromal Alzheimer's Disease; Alzheimer Disease; Preclinical Alzheimer's Disease; Dementia

Treatments: Behavioral: Message; Behavioral: Financial Incentives

Study type: Interventional

Funder types: Other

Identifiers

NCT06033066

UP-22-01037

Details and patient eligibility

About

This single-blind, three-arm, randomized, controlled trial will assess the impact of messages and financial incentives on the enrollment of demographically diverse individuals to the Alzheimer Prevention Trials (APT) Webstudy. The APT Webstudy is a novel, online registry that employs quarterly cognitive testing using validated platforms. The APT Webstudy implements fully remote assessments, coordinated by the Alzheimer's Therapeutic Research Institute (ATRI) under USC IRB #HS-17-00746. The purpose of the current study is to test whether we can increase enrollment of diverse individuals into the registry. To do this, we will work with Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers in Contra Costa County, California, to test whether sending messages with and without financial incentives to patients who receive primary care with the health system can increase enrollment to the APT Webstudy. The investigators hypothesize that 1) a certain small financial incentive and an award opportunity based incentive (or a drawing with a prize) will increase enrollment rates of CCHS members into the APT Webstudy relative to the control group. The investigators further hypothesize that the award opportunity incentive will increase the enrollment rate of CCRMC patients into the APT Webstudy more than a certain financial incentive with the same expected value.

Enrollment: 48,000 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

To be eligible to participate in this study, an individual must meet all of the following criteria:

• Patients empaneled at Contra Costa Regional Medical Center (CCRMC), the county public hospital and its affiliated health centers.
• Age 50 or older
• Literate in either English or Spanish

Exclusion criteria

• Below age 50
• Documentation of prior dementia diagnosis

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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48,000 participants in 3 patient groups

Messaging Only

Active Comparator group

Description:

16,000 participants will be randomized to Arm 1 where no monetary incentive is offered.

Treatment:

Behavioral: Message

Small Incentive

Experimental group

Description:

16,000 participants will be randomized to Arm 2 where a small one-time monetary incentive is offered.

Treatment:

Behavioral: Financial Incentives

Prize Incentive

Experimental group

Description:

16,000 participants will be randomized to Arm 3 where an opportunity based incentive (or a drawing with a prize) with a single winner will be offered.

Treatment:

Behavioral: Financial Incentives