Finger Muscle Reaction After Electrical Stimuli to the Human Finger Pulley System; a Pilot Study

Mayo Clinic

Status: Completed

Conditions: Healthy

Treatments: Procedure: Guided insertion of electrodes; Procedure: Electromyographic (EMG) recording

Study type: Observational

Funder types: Other

Identifiers

NCT01456871

11-004310

Details and patient eligibility

About

The purpose of the study is to gain a better understanding of mechanoreceptors in the PIP joint ligamento-muscular reflexes and their role is.

Full description

Encapsulated nerve endings called mechanoreceptors are end components of afferent nerves and have specialized end organs surrounding the nerve terminal. Those receptors are concentrated in various human periarticular tissues. It is believed that these mechanoreceptors in the periarticular tissues are related to muscle reflexes. However, it is still unknown which type of mechanoreceptors contribute to the muscle reflexes and whether the mechanoreceptors excite and/or inhibit muscle activation. In the investigators previous studies, mechanoreceptors in the human proximal interphalangeal (PIP) joint and surrounding structures have been extensively examined. The investigators have identified that Pacini-like nerve endings in the PIP joint were found in substantial numbers in the junction of the C1 pulley and accessory collateral ligaments. The investigators hypothesize that the Pacini-like nerve endings in the junction of the C1 pulley generate activity in the associated flexor muscle/tendon in the finger.

Enrollment: 6 patients

Sex: Female

Ages: 20 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Females aged 20-30

Exclusion criteria

• A history of any upper extremity injury or disorder in the non-dominant arm
• A history of any neurologic or bleeding disorder, or taking blood-thinning medication.
• Presence of Linbug-Comstock syndrome

Trial design

6 participants in 1 patient group

Healthy adult females

Description:

Females, aged 20 to 30 with no history of upper extremity injury or disorder in the non-dominant arm, no history of neurologic or bleeding disorder, and no evidence of Linburg-Comstock syndrome.

Treatment:

Procedure: Guided insertion of electrodes

Procedure: Electromyographic (EMG) recording