FINRISK 2002 Re-examination

University of Turku

Status: Completed

Conditions: Cardiometabolic Syndrome; Cardiovascular Diseases

Treatments: Other: Health examination; Other: Questionnaire and fecal sampling

Study type: Observational

Funder types: Other

Identifiers

NCT06284772

4457/2023

Details and patient eligibility

About

The project aims to fill in the existing gaps in the study of the microbiome as a cardiometabolic driver 1) by determining the key demographic, environmental, genetic, dietary, and metabolic correlates of long-term within-individual microbiome and microbial metabolite changes; and 2) by assessing how the gut microbiome, microbial metabolites, and their long-term changes are prospectively related to the risk factors, surrogate markers, and overt outcomes of CMD. To achieve this goal, repeat stool samples will be collected of ~2300 Finnish individuals who gave stool samples in the year 2002. In addition, ~300 individuals will undergo a in-depth health examination in 2024.

Enrollment: 2,500 patients

Sex: All

Ages: 47 to 96 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Participation in FINRISK 2002 fecal sampling

Trial design

2,500 participants in 2 patient groups

FINRISK 2002 re-examination cohort

Description:

All still-living FINRISK 2002 participants (\~6000) were invited do participate in a re-examination \>20 years after the initial fecal sampling. 2500 took part in the study.

Treatment:

Other: Questionnaire and fecal sampling

FINRISK 2002 re-examination health examination

Description:

The \~800 still-living participants from the Turku and Loimaa area were asked to participate in a health examination. 269 individuals took part in the health examination.

Treatment:

Other: Questionnaire and fecal sampling

Other: Health examination