Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood

Copenhagen Studies on Asthma in Childhood

Status and phase: Active, not recruiting; Phase 1

Conditions: Asthma; Eczema; Allergy

Treatments: Dietary Supplement: olive oil; Dietary Supplement: n-3 fatty acid

Study type: Interventional

Funder types: Other

Identifiers

NCT00798226

H-B-2008-093

Details and patient eligibility

About

The aim of this study is to prevent asthma and allergies in childhood by supplementation with fish oil (n-3 fatty acids) to the mother during pregnancy. Paticipants are mother and children participating in the ABC-(Asthma Begins in Childhood)cohort. Mothers are recruited during pregnancy and receive supplement with n-3 fatty acids or olive oil (placebo) from week 24 of gestation to 1 week after delivery. The child is followed with acute and planned visit at the research unit and diagnosis of disease is done in the research unit according to predefined algorithms.

Enrollment: 800 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria (mother):

• Pregnant women
• Living in Sealand, Denmark
• Fluent in Danish Language
• Willing to let the newborn child participate in the study

Exclusion Criteria (mother):

• Participating in other clinical trial

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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800 participants in 2 patient groups, including a placebo group

1

Active Comparator group

Description:

n-3 fatty acid

Treatment:

Dietary Supplement: n-3 fatty acid

2

Placebo Comparator group

Description:

Olive oil

Treatment:

Dietary Supplement: olive oil