FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI Phenotype

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Enrolling

Conditions: Glioblastoma

Treatments: Diagnostic Test: Blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT05793021

3751

Details and patient eligibility

About

The aim of this interventional study is to investigate the correlation between Magnetic Resonance Phenotype and levels of FKBP51s protein pre and post surgery in adult patients affected by Glioblastoma

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >= 18 years
• Diagnosis of Glioblastoma with surgery criteria
• Brain MRI with contrast both pre and post surgery

Exclusion criteria

• No availability of radiological documentation
• Glioblastoma diagnosis not confirmed by Histological examination
• Withdrawal of ICF

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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70 participants in 1 patient group

Single arm

Other group

Treatment:

Diagnostic Test: Blood sample