Flapless Emdogain in the Treatment of Periodontal Residual Pockets

Arab American University (Palestine)

Status

Completed

Conditions

Chronic Periodontitis, Generalized

Treatments

Procedure: Re-instrumentation with placebo application

Procedure: Re-instrumentation with flapless Emdogain application

Study type

Interventional

Funder types

Other

Identifiers

NCT05823389

EMD

Details and patient eligibility

About

48 adult patients participated in a single-centre randomized clinical trial with split- mouth design. They had presented at re-evaluation after initial non-surgical periodontal therapy (steps 1 and 2 of periodontal therapy) for generalized periodontitis with at least 2 teeth with residual probing pocket depths (PPD) ≥5 and ≤8 mm, with bleeding on probing (BOP). Two teeth with similar PPD were randomized to receive re-instrumentation either with (test) or without (control) adjunctive flapless administration of EMD. Differences in the changes of PPD and BOP from baseline to 6 and 12 months will be analysed, and the frequencies of pocket closure (PPD ≤4 mm and no BOP) will be compared

Enrollment

48 patients

Sex

All

Ages

19 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

at least two residual pockets with probing pocket depth (PPD) ≥5 and ≤8 mm,
bleeding on probing (BOP),
mobility ≤degree 1 and
no furcation involvement.

Exclusion criteria

full mouth plaque score >20%,
uncontrolled systemic disease,
history of malignant disease in the oral cavity or previous radiotherapy in the head or neck area,
pregnant or lactating females,
drug and alcohol abuse,
smoking >10 cigarettes per day and
inadequate restorative therapy or malocclusion.