Flash Glucose Measurement in Patients on Total Parenteral Nutrition

The Leeds Teaching Hospitals NHS Trust

Status: Unknown

Conditions: Diabetes Mellitus

Treatments: Device: FreeStyle Libre Pro

Study type: Interventional

Funder types: Other

Identifiers

NCT03871660

LeedsNHS

Details and patient eligibility

About

IV nutrition is a means of providing all the nutritional requirements of people who have severe bowel disease. At least 10% of people on longer term IV nutrition also have diabetes and IV nutrition includes delivering glucose directly to large veins. Unsurprisingly this causes elevated blood glucose levels, particularly in people with diabetes. This can make treatment of hyperglycaemia more challenging. As a result this study aims to use a flash glucose monitoring device, the FreeStyle Libre pro, to investigate what happens to glucose levels in patients receiving IV nutrition. We will look at this trend in 5 patients with diabetes and 5 patients without diabetes receiving IV nutrition.

Enrollment: 10 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants receiving TPN in Leeds with or without diabetes

Exclusion criteria

• Patients not receiving TPN
• Patients who do not speak English
• Patients who are unable to give consent

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 2 patient groups

Patients with diabetes on TPN

Other group

Description:

Glucose levels will be monitored using the FreeStyle Libre devices over a 14 day period. In this time the patient will receive TPN.

Treatment:

Device: FreeStyle Libre Pro

Patients without diabetes on TPN

Other group

Description:

Glucose levels will be monitored using the FreeStyle Libre devices over a 14 day period. In this time the patient will receive TPN.

Treatment:

Device: FreeStyle Libre Pro