Florida Cerebrovascular Disease Biorepository and Genomics Center

Mayo Clinic

Status: Enrolling

Conditions: Subarachnoid Hemorrhage; Non-Aneurysmal Perimesencephalic Subarachnoid Haemorrhage; Ischemic Stroke; Asymptomatic Carotid Artery Stenosis; Moyamoya Disease; Leukoaraiosis; Transient Ischemic Attack; Intracerebral Hemorrhage; Reversible Cerebral Vasoconstriction Syndrome; Arteriovenous Fistula; CADASIL; Anoxic Brain Injury; Cerebrovascular Disease; Aneurysmal Subarachnoid Hemorrhage; Vascular Dementia; Carotid Artery Stenosis Symptomatic; Fibromuscular Dysplasia; Cerebral Venous Thrombosis; Unruptured Intracranial Aneurysm

Study type: Observational

Funder types: Other

Identifiers

NCT05491980

22-002667

Details and patient eligibility

About

The purpose of this study is to create a state-wide biorepository and resource center for cerebrovascular diseases in Florida, which will include collecting medical history information and blood from subjects affected by cerebrovascular disease. The information and blood samples collected may be used in future research for the study of cerebrovascular disease and to learn about, prevent or treat other health problems.

Enrollment: 5,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Affected subjects with diverse cerebrovascular conditions, including, but not limited to, ischemic stroke, transient ischemic attack (TIA), intracerebral hemorrhage (ICH), aneurysmal subarachnoid hemorrhage (aSAH), vascular dementia (VAD), anoxic brain injury, unruptured intracranial aneurysm (UIA), cavernous malformation, arteriovenous malformations (AVM), carotid and vertebral arterial dissections, symptomatic and asymptomatic cervical carotid artery atherosclerotic stenosis, non-aneurysmal perimesencephalic subarachnoid hemorrhage (naSAH), cerebral venous thrombosis (CVT), moyamoya disease, fibrosmuscular dysplasia (FMD), non-traumatic, angiography-negative subarachnoid hemorrhage, leukoaraiosis, arteriovenous fistula, reversible cerebral vasoconstriction syndrome (RCVS), and CADASIL.

Exclusion criteria

• All patients with the following known or suspected virulent microorganisms causing an active or latent infection will be excluded from the study:

• Human immunodeficiency virus (HIV);
• Any viral hepatitis;
• West Nile virus (WNV);
• Influenza virus;
• Tuberculosis (TB);
• Any bacteremia;
• Any fungemia;
• Any prionopathy.