Fluid Absorption in Patients Undergoing Operative Hysteroscopy; Results From a Prospective Controlled Study

University of Jordan

Status: Completed

Conditions: Fluid Overload

Treatments: Other: General anesthsia; Other: oxytocin and spinal anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04328870

IORG0007981

Details and patient eligibility

About

To determine if combining intravenous oxytocin infusion and spinal anesthesia will reduce the amount of glycine absorption in patients undergoing operative hysteroscopy

Full description

Prospective controlled study in premenopausal patients who had hysteroscopic surgery including endometrial resection, endometrial polypectomy, myomectomy resection and uterine septal resection. The effect of combined spinal anesthetic with oxytocin infusion on fluid deficit was studied.

Enrollment: 88 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• premenopausal with no cardiovascular comorbidities

Exclusion criteria

• endometrial cancer cases, patients who received pre-operative hormonal preparations, previously resected cases and cases done using bipolar diathermy.

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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88 participants in 2 patient groups

oxytocin and spinal anesthesia

Active Comparator group

Description:

spinal anesthesia combined with intravenous oxytocin infusion

Treatment:

Other: oxytocin and spinal anesthesia

general anesthsia

Active Comparator group

Description:

general anesthesia alone

Treatment:

Other: General anesthsia