Fluid Optimisation in Laparoscopic Colorectal Procedures

University Medical Centre Ljubljana

Status: Completed

Conditions: Perioperative Complication

Treatments: Procedure: Perioperative fluid optimisation

Study type: Interventional

Funder types: Other

Identifiers

NCT04719884

127/5/12

Details and patient eligibility

About

Goal-directed fluid therapy (GDFT) with hemodynamic monitoring may not be of benefit to all elective patients undergoing major abdominal surgery, particularly those managed in Enhanced Recovery After Surgery protocols (ERAS) setting.

Full description

Our study compared two groups of patients undergoing elective laparoscopic colorectal surgery: a control group (CG) in which standard haemodynamic monitoring was used, and a study group (SG) in which extended haemodynamic monitoring was applied with appropriate intraoperative interventions. Differences in intraoperative fluid management, hospital stay, and postoperative morbidity were observed.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients, undergoing elective laparoscopic colorectal surgery

Exclusion criteria

• Patients with cardiac arrhythmias

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Control group

No Intervention group

Description:

Standard perioperative anesthesia management

Study group

Active Comparator group

Description:

Perioperative extended haemodynamic monitoring of fluid loading, cardiac output and changes of peripheral vascular resistance by analysing the arterial curve was provided by non-invasive haemodynamic monitoring (LIDCO Rapid, Lidco Ltd., United Kingdom).In SG fluid optimisation was performed before pneumoperitoneum and after abdominal desuflation with actions to achieved CI, MAP and SI within 80% of baseline values.

Treatment:

Procedure: Perioperative fluid optimisation