Fluid Requirement During Surgery PVI v Doppler (PVIvDoppler)

York Teaching Hospitals NHS Foundation Trust

Status

Completed

Conditions

Major Abdominal Surgery

Colorectal Surgery

Treatments

Device: Doppler

Other: PVI'

Study type

Interventional

Funder types

Other

Identifiers

NCT02142816

YOR-A02089

Details and patient eligibility

About

Targeting the amount of fluid given to measurements of the patients own fluid status during major abdominal surgery has been linked with improved speed of recovery of gut function and reduced length of hospital stay, mortality and complications.

Pleth variability index (PVI) offers a noninvasive, risk and pain free alternative to more invasive forms of monitoring to direct how much fluid to give.

The study aims primarily to measure and compare how much fluid is given when guided by PVI compared to the established technique; oesophageal doppler during major abdominal surgery.

The study will compare 40 patients undergoing major elective abdominal surgery. Patients will receive intraoperative fluid guided by either oesophageal doppler or PVI. Secondarily, the study will examine biochemical markers, length of hospital stay and how frequently complications occur

Enrollment

38 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Major abdominal surgery
Anaerobic Threshold >11 ml O2/kg/min
VE/VCO2 <34 OR
Low risk according to Consultant anaesthetist

Exclusion criteria

Patients age less than 18
Patient refused consent
Patient unable to give consent
Patient has had <24hrs to consider the Patient information Sheet
Contraindication to Doppler Probe being inserted
Emergency Procedure
Patient has a ASA Grade 5
Patient is receiving dialysis treatment
Patient has a known hypersensitivity to hydroxyethyl starch or gelatin solutions
Patients with renal failure with oliguria or anuria - not related to hypovolaemia
Patients with a previously diagnosed dysrhythmia
Patients who weight >100kg