Fluid Restriction After Stapled Hemorrhoidopexy

Tri-Service General Hospital

Status: Completed

Conditions: Fluid Restriction

Treatments: Drug: 1000 mL 0.9% sterile saline; Drug: 250 mL 0.9% sterile saline

Study type: Interventional

Funder types: Other

Identifiers

NCT04459039

2-106-05-063

Details and patient eligibility

About

BACKGROUND: Conventional hemorrhoidectomy leads to a high urinary retention rate and fluid restriction is commonly recommended to minimize complications. However, the need for postoperative fluid restriction among patients who have undergone stapled hemorrhoidopexy is unclear. We aimed to determine whether fluid restriction after stapled hemorrhoidopexy with/without partial external hemorrhoidectomy could reduce urinary retention and postoperative pain.

PATIENTS AND METHODS: In this prospective, double-blinded, randomized controlled trial, we enrolled patients who had grade III or IV hemorrhoids and underwent stapled hemorrhoidopexy with/without partial external hemorrhoidectomy; 250 mL/12 h of sterile 0.9% saline was administered to the fluid restriction group after the operation, and 1000 mL/12 h was given to the non-fluid-restriction group. We focused on the need for fluid restriction after stapled hemorrhoidopexy.

Enrollment: 53 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Gr. III-IV hemorrhoids paitents

Exclusion criteria

• Age<20 or >80
• Allergy to NSAID or opoids
• Impaired renal function
• Pregnant or breast feeding

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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53 participants in 2 patient groups, including a placebo group

Fluid restriction

Experimental group

Description:

Within 12 h of surgery, the experimental group received 1000 mL 0.9% sterile saline intravenously.

Treatment:

Drug: 1000 mL 0.9% sterile saline

Non-fluid restriction

Placebo Comparator group

Description:

Within 12 h of surgery, the control group received 250 mL 0.9% sterile saline intravenously

Treatment:

Drug: 250 mL 0.9% sterile saline