Fluorescein Angiography in Patients With Diabetes and Chronic Kidney Disease (Fluo-AKI)

Saint-Joseph University

Status

Not yet enrolling

Conditions

Acute Kidney Injury

Diabetes Mellitus

Chronic Kidney Disease Stage 3B

Chronic Kidney Disease Stage 4

Chronic Kidney Disease Stage 5

Fluorescein Angiography

Treatments

Diagnostic Test: Fluorescein angiography

Study type

Interventional

Funder types

Other

Identifiers

NCT06760650

Tfem-2025-79 (Other Identifier)

CEHDF 2587

Details and patient eligibility

About

Our study hypothesizes that fluorescein exposure in diabetic patients with advanced chronic kidney disease results in deterioration of kidney function. It will therefore aim to evaluate the incidence of acute kidney injury induced by fluorescein in diabetic patients with CKD. The objective is to determine the incidence, severity and risk factors associated with this deterioration to improve the care of this specific population.

Full description

This study will assess the change in serum creatinine in patients with diabetes and advanced chronic kidney disease, after a fluorescein angiography. This is a before and after study that will include 35 patients from the department of ophtalmology over 6 months with a total follow-up for 3 months.

Enrollment

35 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

>18 years old with type 2 or type 1 diabetes and chronic kidney disease stage 3b to 5 (eGFR<45 mL/min/1.73 m2)

Exclusion criteria

Patients who do not give their consent
Patients who are allergic to fluorescein
Patients who are on dialysis
Patients who had fever, vomiting, diarrhea or any dehydration 48 hours before the intervention
Patients who had a treatment modification one week before the intervention