Fluorescence-navigated Thoracoscopy for Pulmonary Segmentectomy

Peking University

Status: Unknown

Conditions: Pulmonary Segmentectomy

Treatments: Procedure: Indocyanine Green Injection through Peripheral Vein

Study type: Interventional

Funder types: Other

Identifiers

NCT04160884

2018PHB143-01

Details and patient eligibility

About

Recently developed fluorescence-navigated thoracoscopy with indocyanine green (ICG) is being used for various kinds of pulmonary surgery, and several studies have reported the application of this novel technique in demarcation of the intersegmental border for segmentectomy. This study is performed prospectively to find out, for the first time, the optimal dosage of ICG in human body to ensure safe and sustained imaging during segmentectomy.

Enrollment: 68 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Suitable for segmentectomy and signed informed consent

Exclusion criteria

• Liver dysfunction.
• Allergic to indocyanine green.
• Can't tolerate thoracoscopic surgery.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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68 participants in 2 patient groups

A

Active Comparator group

Description:

0.6mg/kg of ICG, iv

Treatment:

Procedure: Indocyanine Green Injection through Peripheral Vein

B

Experimental group

Description:

0.2mg/kg of ICG, iv

Treatment:

Procedure: Indocyanine Green Injection through Peripheral Vein