Focused Assessed Echocardiography to Predict Fluid Responsiveness (fluidres)

L

Lithuanian University of Health Sciences

Status

Completed

Conditions

Hypotension
Hypovolemia
Surgery

Treatments

Diagnostic Test: Fluid challenge
Diagnostic Test: Focused transthoracic echocardiography

Study type

Interventional

Funder types

Other

Identifiers

NCT03044405
ECHO2

Details and patient eligibility

About

The aims of the study are: To evaluate the feasibility of echocardiography monitoring in postoperative unit; To assess diagnostic value of different focussed echocardiography parameters to define fluid responsiveness for non-cardiac hypotensive spontaneously breathing patients after major abdominal surgery.

Full description

As there are different strategies of perioperative fluid management discussion which is the choice liberal or restrictive one occurs? Individualized infusion therapy should be the goal. The investigators hypothesize extended hemodynamic monitoring based on focused transthoracic echocardiography enable to differentiate the cause of hypotension more carefully and fluid overload will be avoided after major abdominal surgery. The goals of the study are: To conduct one group of hypotensive patients after major abdominal surgery. To divide this group into responders and nonresponders after fluid challenge. To evaluate the feasibility of echocardiography monitoring in postoperative unit (having in mind such restrains as supine position, postoperative pain, bandages etc.) To compare the evaluation of fluid responsiveness by clinical signs and focused assessed echocardiography data. To identify the best focused echocardiography parameters for prognosis of fluid responsiveness. To determine if extended hemodynamic monitoring changes postoperative fluid management.

Enrollment

40 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age more than 18 years old.
  • Patients who sign an agreement form to participate in the study.
  • Patients undergoing major abdominal surgery.
  • Hypotension

Exclusion criteria

  • Younger than 18 years old.
  • Known pregnancy.
  • Unconscious patients or those who do not agree to participate in the study.
  • Urgent surgery.
  • Normal arterial blood pressure.

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

40 participants in 1 patient group

Responders and non-responders
Other group
Description:
Fluid challenge of 500 ml of crystalloids over 15 minutes is given. Positive fluid responsiveness is defined by an increase in stroke volume (SV) of at least 15% assessed by focused transthoracic echocardiography.
Treatment:
Diagnostic Test: Focused transthoracic echocardiography
Diagnostic Test: Fluid challenge

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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