Follicular Fluid Fetuins in in Vitro Fertilization

Samsun Education and Research Hospital

Status: Completed

Conditions: Infertility; Infertility, Female

Treatments: Diagnostic Test: Serum test

Study type: Interventional

Funder types: Other

Identifiers

NCT04201847

KAEK-2019/4/27

Details and patient eligibility

About

This study aims to investigate whether follicular fluid concentrations of fetuin A and fetuin B are associated with the clinical pregnancy and live birth rates in in vitro fertilization (IVF) cycles.Twenty-nine women with poor ovarian reserve (poor responders) and 33 women with polycystic ovary syndrome (hyper responders) who consecutively underwent IVF at a private hospital between May 2018 and February 2019.Fetuin A and fetuin B in follicular fluid were significantly lower in women who had clinical pregnancy than women who had no clinical pregnancy (p=0.001 for both)

Enrollment: 96 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

Poor ovarian reserve patients and patient with polycystic ovary syndrome

Exclusion criteria

Normoresponders

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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96 participants in 3 patient groups

Infertile women with normal ovarian reserve

Active Comparator group

Description:

Infertile women with normal ovarian reserve will be included.

Treatment:

Diagnostic Test: Serum test

Infertile women with high ovarian reserve

Active Comparator group

Description:

Infertile women with high ovarian reserve will be included.

Treatment:

Diagnostic Test: Serum test

Infertile women with poor ovarian reserve

Active Comparator group

Description:

Infertile women with poor ovarian reserve will be included.

Treatment:

Diagnostic Test: Serum test