Follow-up of a Cohort of Patients With Aortic Valve Bicuspidia

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Aortic Valve, Bicuspid

Treatments: Other: Study the natural history of bicuspid

Study type: Observational

Funder types: Other

Identifiers

NCT03139786

PI2012_843_0014

Details and patient eligibility

About

The aortic valve bicuspidia (BVA) is a congenital condition corresponding to the presence of 2 sigmoids instead of 3. This is the most common cardiac congenital anomaly affecting 0.5 to 2% of the population The general rule. BVA may be associated with structural damage to the ascending aorta, which exposes BVA patients to a risk of developing ascending aortic aneurysm and acute aortic accidents. Recent data from the literature have revealed that the natural history of BVA is marked by a possible development towards significant valvulopathy and / or an ascending aortic aneurysm often requiring surgical treatment. However, the natural history of bicuspid disease remains poorly understood and the prognostic factors for progression to severe valvulopathy and / or aneurysmal dilatation of the ascending aorta remain to be determined.

Enrollment: 232 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients examined in the echocardiography laboratory whose objective examination was a bicuspid valve of the aortic valve
• Bicuspidia may be formerly known

Exclusion criteria

• Refusal to participate
• Patients who had already undergone bicuspid surgery or ascending aorta before being examined at the echocardiography laboratory