Follow Up of High Risk Hodgkin Lymphoma in First Complete Remission (HOLYFU)

Federico II University

Status: Completed

Conditions: Hodgkin Lymphoma; Relapse; High Risk

Treatments: Diagnostic Test: Imaging cohort: integrated imaging follow-up; Diagnostic Test: Standard cohort: Clinical lab follow-up

Study type: Observational

Funder types: Other

Identifiers

NCT04298619

HEM-FEDII-HL follow-up -001

Details and patient eligibility

About

Cohort study enrolled high-risk Hodgkin Lymphoma patients in first relapse after induction therapy followed after remission either with a systemic imaging-based surveillance (Imaging cohort) or with standard clinical-based surveillance (standard cohort).

Enrollment: 123 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• High risk Hodgkin Lymphoma
• achievement of complete response to first line therapy

Exclusion criteria

• comorbidities that could impair participation in follow-up procedures

Trial design

123 participants in 2 patient groups

Standard cohort

Description:

Clinical-based surveillance after first complete remission in High risk Hodgkin Lymphoma patients: * symptom assessment * blood tests * physical examination

Treatment:

Diagnostic Test: Standard cohort: Clinical lab follow-up

Imaging cohort

Description:

Clinical-based surveillance after first complete remission in High risk Hodgkin Lymphoma patients: * symptom assessment * blood tests * physical examination * Positron Emission Tomography (PET)/Computed Tomography (CT) or Chest X-Ray ultrasonography scan of superficial, mediastinal, abdominal and pelvic lymph nodes

Treatment:

Diagnostic Test: Standard cohort: Clinical lab follow-up

Diagnostic Test: Imaging cohort: integrated imaging follow-up